Tasks are linked with dependency lines on the chart Here’s a spreadsheet that looks a bit Gantt-y. It’s not strictly speaking a ‘real’ Gantt chart, but it is good enough as as a communication tool for most stakeholders, especially in teams where there is low project management maturity and they aren’t used to looking at the real thing. This spreadsheet version was created with Gantt Excel, a cost-effective plugin that turns Excel into something that functions as a Gantt chart, with virtually no learning curve! DIY versionĪn even simpler option is to use Excel to mock up what looks like a Gantt chart. It’s clean, colorful and shows everything you would expect from a Gantt chart in a very user-friendly way. Here’s an example of how a Gantt chart Excel schedule can look. It’s easy to understand and easy to use, because most stakeholders are already familiar with the concept of spreadsheets. Why use Excel? We need to be realistic about our teams’ and stakeholders’ capability to review and understand Gantt charts at all. But I do have something to share with you that will magically make it into a Gantt chart tool. I’ve been asked that a lot! OK, OK, I know that Excel is not a traditional Gantt chart tool. Watch this video for a short tutorial on how to create a Gantt chart with Office Timeline PowerPoint plugin. If you create a lot of status reports in PowerPoint, this is a simple way of designing Gantt charts for communication purposes direct on your slides. It’s as easy to use as the rest of PowerPoint. You can choose dates, set milestones and show progress (showing progress is only an option with the paid version). It’s Gantt chart creator software that lets you create neat Gantt charts from within PowerPoint itself. Office Timeline is a clever free plugin for Microsoft PowerPoint. Let’s get started! Method #1: Make a Gantt Chart with Office Timeline PowerPoint Plugin In the article you’ll also find out what has to go in your Gantt chart to make it fit for purpose, and I’ll share some other tips for working with Gantt charts. ![]() ![]() It’s a subscriber-only benefit and you’ll get access to over 20 free project management templates and resources to help you keep your projects and career on track. Get a free basic Gantt Chart Excel template in my project management resource library. There’s another graphics package I use to create Gantt charts for presentations as well, Vizzlo. I can help! In this article you’ll learn how to create Gantt charts using PowerPoint and Excel: tools you most likely already have. So what do you use instead? Or what can you use if your project doesn’t warrant a massive Gantt chart? Or if you want to use a Gantt chart but you don’t have any specialist software to create one? The Gantt chart format is often a poor way to communicate to stakeholders. But MS Project, and tools like it, are often overkill for project stakeholders who don’t care about all the detail. I have used Microsoft Project for many years and it creates great Gantt charts. Even if you don’t manage projects but are involved in project teams, or you manage Agile projects – Gantt charts are everywhere. If you manage projects, you will have come across a Gantt chart.
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Top images of middle finger pose by website compilation. Communication is not reserved for hearing people alone, and using one’s voice is not the only way to communicate. They use sign language, lip-reading, vocalizations, and so on to communicate. Deaf, DeafBlind, DeafDisabled, Hard of Hearing, and Late-Deafened people are by no means “silent” at all. The term is offensive for a number of reasons. In later years, “dumb” came to mean “silent.” This definition still persists, because that is how people see deaf people. ![]() (Source: Deaf Heritage, by Jack Gannon, 1980). To his way of thinking, if a person could not use voice in the same way as hearing people, then there was no way that this person could develop cognitive abilities. Deaf and Dumb - A relic from the medieval English era, the Greek philosopher, Aristotle, pronounced us “deaf and dumb,” because he felt that deaf people were incapable of being taught, of learning, and of reasoned thinking.However, there have been alternative terms used which are often seen in print, heard on radio and television, and picked up in casual conversations all over. ![]() What is wrong with the use of these terms “deaf-mute,” “deaf and dumb,” or “hearing-impaired”?ĭeaf, DeafBlind, DeafDisabled, Hard of Hearing, and Late-Deafened people have the right to choose how they wish to be identified, either as a group or on an individual basis. Whatever the decision, the NAD welcomes all Deaf, deaf, hard of hearing, late-deafened, and DeafBlind Americans, and the advocacy work that the NAD does is available to and intended to benefit everyone. It’s all about choices, comfort level, mode of communication, and acceptance. Individuals can choose an audiological or cultural perspective. Over the years, the most commonly accepted terms have come to be Deaf, DeafBlind, DeafDisabled, Hard of Hearing, and Late-Deafened. Other people identify themselves as DeafBlind which usually indicates that they are deaf and also have some degree of vision loss. How people identify themselves is personal and may reflect identification with the deaf communities, the degree to which they can hear, or the relative age of onset. For example, some people identify themselves as Late-Deafened indicating that they became deaf later in life. There are variations in how a person becomes deaf, level of hearing, age of onset, educational background, communication methods, and cultural identity. What is the difference between a person who is deaf or hard of hearing?ĭeaf communities are diverse with people identifying as Deaf, DeafBlind, DeafDisabled, Hard of Hearing, and Late-Deafened. Early Intervention for Infants and ToddlersĬommunity and Culture – Frequently Asked Questions.State Association and Affiliate Committee.To register or find details on individual courses, select the course title below. Additional outside resources for persons who are deaf or hard of hearing can be found through the WI Department of Health Services Office for the Deaf and Hard of Hearing or the National Association of the Deaf. Our ASL course curriculum is designed for adult learners who are hearing capable. Join us in embracing the beauty and intricacies of ASL communication and the vibrant world of the deaf community. ![]() Whether you’re starting your ASL journey or seeking to deepen your skills, there’s a perfect level for you. Our program celebrates this aspect, providing a platform where hearing individuals can learn ASL while gaining insight into and appreciation for deaf culture. ASL is a vibrant language complete with its own grammar, syntax and nuanced terminology, making it a fascinating linguistic journey for everyone.ĪSL is a language that transcends barriers, relying on visual cues such as eye contact, facial expressions and body movements for effective communication. Discover the rich world of American Sign Language (ASL) at the UWM School of Continuing Education, where our courses offer more than just learning signs. ![]() Our left channel was cutting out constantly. The same preamps that fizz and sounded like mud. The same preamps that Mackie talks famously about. By the third new speaker set for the FOH, we realized that it was the preamps. At the time we didn't know any better we thought it was the speakers. ![]() From day one it sounded like we were singing through a wet blanket. The biggest piece of dog doo doo I've ever used. Not sure about Mackie gear in the studio but DITTO regarding the Mackie VLZ Pro live. call your manufacturer on their out of spec firewire port problem and complain until they fix your issue or replace your laptop. exists and causes any firewire adapter to not function properly that is the fault of the laptop manufacturer not mackie. their hardware is designed and needs a certain amount of bandwidth and latency headroom. So a guy had an irq conflict in his laptop he couldn't resolve and that was causing interference with the firewire port. does that mean these items represent the build quality of the actual product for the entire line? In every case there is always going to be a problem with one item or another off the assembly line of any manufacturer. I know plenty of people with mackie mixers and their studio monitors as well as p.a. this thing is over a decade old and still works well and sounds clean. no isues other than needing to clean it once in a while. I have a mackie cr 1604 that is still functioning fine. ![]() Also, a number of web services are commonly available that can help you with this task.įinally, the best way to generate random emails depends on your specific needs.Using a combination of the above methods.Create a dictionary of real email IDs and randomly select one from it. ![]() Using a random number generator to produce the user name and domain name. ![]() In addition to the methods you have seen, there are some more ways to do it. See also Python List Contains Elements of Another List Other ways to generate random email It then creates random email addresses by predicting the next character based on the previous one. Random_email = generate_random_email_markov(markov_chain)Įxplanation: This code creates a Markov chain model from a list of sample emails. Sample_emails = build_markov_chain(sample_emails) Start = random.choice(list(chain.keys())) import randomĭef generate_random_email_markov(chain, length=10): ![]() In contrast to previous approaches, Markov chains can also generate email addresses for a more human-like touch.Īpproach: We’ll build a Markov chain model based on existing email IDs to create new ones. Random_email = generate_random_email_uuid()Įxplanation: This code employs the uuid module to create a unique identifier, shortening it to the first 10 characters, and finally appending the domain to craft a random email address. import uuidĭomain = str(uuid.uuid4()).replace("-", "") Using UUID and domainįorming unique email addresses by combining a UUID (Universally Unique Identifier) with a domain.Īpproach: We’ll use the uuid module to generate a UUID and then combine it with a fixed domain. You may even like this tutorial on how to generate a list of random integers in Python. from faker import FakerĮxplanation: By utilizing the Faker library, the above code produces random email IDs that are more real, complete with appropriate domains. The below code helps to illustrate the same. We can use the faker.Faker() function to create a Faker object, which we can then use to generate random email addresses.Īpproach: We’ll install and employ the Faker library to enable random email generation. The Faker library is a 3rd party library that provides functions for creating dummy data, such as names, addresses, and email IDs. See also Your Ultimate Guide to Python List Slicingīy the way, check out if you are keen to know more about random numbers in Python. Subsequently, the domain is appended to produce a completely random email address. Username = ''.join(random.choice(string.ascii_lowercase) for _ in range(username_length))Įxplanation: In this code, a random username with a length between 5 and 10 characters is created using lowercase letters. In Python, we can generate random strings and combine them into email-like addresses.Īpproach: We’ll include Python’s random module to craft random characters into a string similar to an email address. Here are a few of the most common methods: Using random strings
![]() Then you stir in your cheese and milk until melted and creamy. When you open your pot, your pasta is cooked, there’s no water to drain and your pasta already has all the seasonings infused into it. They cook at high pressure in less than five minutes. You add your water, butter, seasoning and pasta into the pot. Making macaroni and cheese has never been easier. I don’t think I will ever go back to making macaroni and cheese on the stove again as long as I have my Instant Pot around. Everything cooks in the pressure cooker so there’s minimal clean-up, too. You can have homemade mac and cheese in 20 minutes with minimal work. Consider adding cooked chicken or sausage, crumbled bacon, diced ham, chopped scallions, sauteed mushrooms, diced tomatoes, sun-dried tomatoes, olives, or sauteed onions and mushrooms.Instant macaroni and cheese is so creamy, easier, and faster than making it on the stove. Variations: There are so many great ways to dress up your mac and cheese. Jamie’s Spice Mix is delicious as is Everything Seasoning. You can leave it with just salt and pepper or add a favorite spice blend. Salt and black pepper – Season according to your tastes. They all taste delicious in Instant Pot Mac and Cheese. Feel free to experiment with different styles of cheese, such as pepper jack, Havarti, or dill Havarti. ![]() Sharp cheddar cheese – Sharp cheeses have more flavor which means you can use less and reduce the cost of the dish. It’s got a higher fat content which makes it less sour tasting. Wanting to reduce the fat content and increase the protein, I started playing with Greek yogurt as a substitute. I found that we liked this just as well, particularly when I use 5% Fage Greek yogurt. ![]() Plain Greek yogurt (fuller fat is best) – I adapted this recipe from my casserole-style recipe that calls for sour cream. Water – I use water for my Instant Pot Mac and Cheese, but if you want more flavor, you can use low sodium chicken broth. Whatever you use, be sure to read the noodle packaging to adjust the cook time accordingly. Here’s what you’ll need to make Instant Pot Mac and Cheese:Įlbow macaroni – I prefer using the large elbow macaroni, but you can also use another tube pasta or your favorite whole wheat pasta. It makes for a great Lunchtime Meal Prep that’s ready in a flash. When I crunched the numbers, I found out that the entire meal costs just a few dollars to feed my whole family. Often I’ll serve this on its own with a quick side salad. I’ve been slow to adopt the electric pressure cooker, but I’ve enjoyed adapting our favorite recipes to be budget-friendly pressure cooker recipes. I feel like I’m not doing anything! Seriously, making Instant Pot Mac and Cheese was a revelation to me. This Instant Pot Mac and Cheese is the perfect meatless meal or side dish for meat and makes dinner prep so incredibly easy – just one pot to wash. This one wins the prize for easiest, most hands-free mac and cheese recipe ever! Imagine no heavy pot of water to drain, no gunky colander to wash! Everything cooks in the same pot for easy prep and simple clean up, making for an ideal side dish or meatless main. All are delicious and easy on the budget, but this one? I’ve got my pet recipes, of course - Baked Mac and Cheese, this easy, creamy Stovetop Mac and Cheese, and my mac with an Italian twist, Alfredo Mac and Cheese. While I do have a nostalgic affection for boxed macaroni cheese dinner, I well know that homemade mac is so much better than anything that comes in a box. Mac and Cheese is pretty easy to make, right? Open the blue box, dump the noodles in boiling water, and mix the dry powder with milk and butter…. ![]() Also, please let me unlock you and you be able to do zero percent of any of your moves in the boss battle. Please let me drill away at you with my best character for fifteen minutes while you go through my unblockable attack with a simple punch button and self-heal yourself and KO me in that singular move. Oh, thanks for changing into the fucking Grim Reaper, Zasalamel. But this was Soul Calibur, a game where you could strip the clothing off of a female character and either be able to decently cover the entire population of Tokyo, or else not be able to decently cover an infant.Īlso, the final boss cheated like a motherfucker. And if I wanted to make a samurai, I had two different styles of armour and three different faces to choose from, but if I wanted to make a whore, I had literally forty different styles of panties I could put on her and five different styles of innocent anime eyes I could customize to my heart's content. This was most obvious in the brand-new "Create-A-Calibur" mode which allowed you to fashion your own character who, no matter how much clothing and accessories you put onto them, because of the stipulation, would still end up looking more boring than the moderator of a livejournal Mucc community. They either needed a singular button press to KO your opponent and get to the "me-so-happy" jiggle victory masturbation dance, or they were made based around an awesome moveset but looked pretty much like if a Playboy Playmate threw up on the DVD collection of an Asian enthusiast who couldn't locate Asia on a map of Asia. This was not more evident than in the new character additions. Girls in costumes that were either practically nonexistant or halting enough to make you wonder how and why they got them on would jump, excuse me, bounce around giggling and moaning as they wrapped their legs around their opponents and went into some sort of automatic-pause for the sole purpose of freezing the screen on a meaty young caucasian woman flashing some leather panties as her leg went over her head and somehow made her breasts jiggle in the process. With Soul Calibur IV looming, all we can do is look back and say "How did it come to this?"Īround the time of Soul Calibur III, the game series seems to have deteriorated into a dating sim that included men and no actual nudity. The majority of this review will focus on the third installment of the game, which is the most mind-fucking of the series, the upcoming game, whose costumes seem to visually make the statement of "fuck this costume, I'm tired", and a look back at some old favourites.Before we begin, let's learn about this series. And, to keep your attention and resist going insane, it will be a fashion review as well!ĭid you think that Tira's costume was impossible and the stuff of nightmares (no pun intended)? That was probably the most normal thing you will see in this game. There is a lot about that series that needs to be shared, and since I think most people may not be as aware of the ultimate horror of it, I will share it with you. ![]() I enjoyed doing my previous entry, and talking about Soul Calibur got me thinking. So, since video gaming has been taking up my time, in some way I guess I will make up for it by bringing the distraction to you for your benefit. I shouldn't be neglecting this, should I? I almost missed IMPORTANT INFORMATION about. Holy crap, it's June already? It doesn't feel like it at all. 2A, the mean BUN level varied and increased steadily with age in males and females populations. The study conforms to the principles outlined in the Declaration of Helsinki and written informed consent was obtained from all participants.įull size image The relation between BUN values and ageĪs showed in Fig. The study was approved by the Ethics Committee of Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology (The Institutional Review Board Approval Number: TJ-C20160115). The exclusion criteria included 10 indicated collinearity among the variables 11. For participants less than 18 years old, their informed consent was obtained from their parents or legal guardians. The included study subjects aged between 14 and 85 years and were considered healthy after a physical examination. The study was performed at the Department of Health Management Center and approved by the Ethics Committee of Tongji Hospital, Huazhong University of Science and Technology. Thus, establishing age- and gender-specific reference intervals for BUN for the local population is critical and of utmost importance. To accurately diagnose the patient's condition and avoid subjective factors, it is necessary to evaluate accurately whether the BUN value is within the normal range. Most clinical laboratories establish the reference intervals from medical literature or the diagnostic test manufacturer 9, 10. Few studies have been performed to establish reference intervals for serum BUN, taking into account the difference between gender and age 8.Īt present, the clinical reference range value of BUN is non-standard and not uniform, both nationally and abroad. However, the value of serum BUN between males and females differ, irrespective of the same age group. These findings indicate that the level of BUN in serum may change dynamically with age. Some studies suggested that elderly females showed a higher protein synthesis rate compared to males, although females have less muscle mass 6, 7. With an increase in age, there is a sex difference in protein turnover. Several studies reported that environmental and other factors, such as geographical change, climate change, gender, age, dietary structure, physical functioning affect BUN values 5. They suggested that BUN plays an essential role in predicting cardiovascular events caused by acute heart failure and is a prognostic or a neurohormonal activation biomarker in heart failure 3, 4. found that BUN predicts survival in patients admitted with heart failure (HF) and not creatinine 2. Therefore, BUN plays a vital role in diagnosing and evaluating renal function 1. The blood BUN level is mainly dependent on its rate of glomerular filtration and tubular reabsorption. Similar content being viewed by othersīlood urea nitrogen (BUN) is a nitrogenous end product of protein metabolism and also produced in the liver by the breakdown of dietary proteins. These results indicate that the serum BUN reference value is significantly affected by age and gender, and thus, its interpretation is age- and sex-dependent. ![]() The BUN values corresponding to the 1st, 2.5th, 50th, 97.5th, and 99th percentiles for any specific age in both sex were also calculated. Thus, the serum BUN values increased by 0.21 mmol/L for males and 0.282 mmol/L for females per 10 years. Multiple linear regression analysis confirmed that the positive associations of BUN levels and age were statistically significant after adjusting confounding factors ( P < 0.001). However, eGFR showed a negative correlation with the BUN reference value (P < 0.0001) in both sexes. BUN values showed a positive correlation with body mass index (BMI), cholesterol, and blood sugar (P < 0.0001). Males had a higher median BUN value compared to females (4.6 mmol/L vs. A total of 24,006 BUN values from healthy adults (14,148 males and 9858 females) were included in the cross-sectional study. This study aims to explore the age- and sex-specific distribution of BUN among healthy Chinese adults. Blood urea nitrogen (BUN) is a nitrogenous end product of protein metabolism. ![]() We describe potential molecular mechanisms in the form of epigenetic modifications that may underlie the transmission and inheritance of traits and highlight the current controversy regarding these concepts. In the remainder of this review, we select examples from studies in rodents modeling the intergenerational and transgenerational transmission of environmentally induced phenotypes with regard to psychiatric phenotypes. Epigenetic mechanisms of gene regulation have been posited as being critical to such transmission and inheritance. Besides direct exposure to stress both in utero and in early life, recent studies in rodents also point toward a transmission, and even inheritance, of environmentally accumulated risk factors via the germline that may occur prior to conception. However, animal models, in contrast, provide valuable insights into the molecular mechanisms of how the environment contributes to risk and resilience. Human studies using a cross-sectional design can and have investigated the overall influence of severe stress or childhood abuse on the risk for psychiatric disorders without having access to neuronal tissue for further analyses. ![]() These factors can exert a profound influence on disease trajectories when they occur during vulnerable periods in brain development like in utero development and early life until completion of adolescence, subsequently increasing the risk for mental health problems in adulthood ( Kessler et al, 1997 Kendler et al, 2000). Such factors have regained attention in the post-genomic era in recent years. Alternative models such as gene by environment interaction studies take this dual influence into account and may provide more insight into the pathophysiology of these disorders in the future ( Klengel and Binder, 2013a Manuck and McCaffery, 2014 Zannas, Wiechmann, Gassen and Binder, this issue).Įnvironmental factors influencing the long-term risk for psychiatric disorders have been known for centuries. The underlying reasons likely involve a larger genetic, but also phenotypic, heterogeneity and a stronger influence of the environment ( Levinson et al, 2014). Additionally, several other moderately powered GWAS have begun to identify genome-wide level significant findings ( Guffanti et al, 2013 Logue et al, 2013 Nievergelt et al, 2015). ![]() The genomics of PTSD is more nascent, and it is too early to tell which trajectory this disorder will have with regards to genetic contribution, though twin studies suggest up to 40% heritability. In contrast to the successful genetic studies for schizophrenia or bipolar disorder ( Schizophrenia Working Group of the Psychiatric Genomics Consortium, 2014 Muhleisen et al, 2014), studies on depression so far have failed to identify reliable genetic markers at sample sizes at which first loci in schizophrenia were identified ( Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium, 2012). Although much effort is spent on studies investigating the genetic basis of psychiatric disorders and outstanding emerging studies point toward a polygenic risk to disease ( Schizophrenia Working Group of the Psychiatric Genomics Consortium, 2014), the overall contribution of genetic factors appears to be rather small in particular for stress and fear disorders based on our current knowledge ( Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium, 2012 Sullivan et al, 2012 Wray et al, 2012 Lee et al, 2013 Levinson et al, 2014). It is widely accepted that environmental and genetic factors contribute to the development of psychiatric disorders. Our understanding of the molecular mechanisms of risk and resilience for disease is pivotal for the development of effective preventative and therapeutic strategies that are superior to the currently available limited therapies. Additionally, stress-related disorders demand increasing medical and economical resources and are predicted to become the leading cause of disability worldwide in the near future ( Wittchen et al, 2011 Whiteford et al, 2013). Changing environmental conditions with respect to not only socioeconomic status, social interactions, trauma exposure, and workload, but also nutritional status, may contribute to this phenomenon and thus potentially lead to a self-reinforcing risk for disease. The pervasiveness of these disorders is increasing in the public perception and recent studies support this view, although there is some controversy with regard to the underlying causes ( Heimberg et al, 2000 Kessler et al, 2005 Compton et al, 2006 Hidaka, 2012). ![]() Stress-related psychiatric disorders such as major depression, posttraumatic stress disorder (PTSD), and other anxiety disorders are highly prevalent in the general population ( Kessler et al, 2005), with an even higher prevalence in military and socioeconomically disadvantaged populations ( Hoge et al, 2004 Gillespie et al, 2009). |
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